This medicine contains the active ingredient reboxetine, which is a type of antidepressant known as a selective noradrenaline re-uptake inhibitor. When depression occurs, there may be a decreased amount of a chemical called noradrenaline released from nerve cells in the brain. When noradrenaline is released from nerve cells it acts to lighten mood. When it is reabsorbed into the nerve cells, it no longer has an effect on mood. Reboxetine works by preventing this re-absorption of noradrenaline back into the nerve cells. Therefore, it helps prolong the mood-lightening effect of any released noradrenaline. This helps relieve depression. Reboxetine must be taken for up to three to four weeks before benefits of treatment may appear.

Medicines and their possible side effects can affect individual people in different ways. The following are some of the side effects that are known to be associated with this medicine. Because a side effect is stated here, it does not mean that all people using this medicine will experience that or any side effect:

Constipation
Dry mouth
Difficulty in sleeping (insomnia)
A drop in blood pressure that occurs when going from lying down to sitting or standing, which results in dizziness and lightheadedness (postural hypotension)
Impotence
Sweating
Balance problems involving the inner ear (vertigo)
Pins and needles (paraesthesia)
Difficulty in passing urine (urinary retention)
Noticeably increased heart rate (symptomatic tachycardia)
The side effects listed above may not include all of the side effects reported by the drug's manufacturer.