Efudex (Fluorouracil) Cream skin medication is an antimetabolite used to treat actinic (solar) keratoses, which is a skin growth caused by exposure to sunlight. Efudex (Fluorouracil) may also be used for other conditions as determined by your doctor.
Efudex side effects include reddening, itching, burning, pain or soreness, tenderness, scaling, or swelling. Check with your doctor if these Efudex side effects are severe. CONTACT YOUR DOCTOR IMMEDIATELY if you experience Efudex side effects like abdominal pain, bloody diarrhea, vomiting, or chills.